KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYAR
All Species:
36.36
Human Site:
Y340
Identified Species:
57.14
UniProt:
Q9NX58
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX58
NP_001139197.1
379
43615
Y340
R
K
K
V
L
A
Q
Y
Y
T
V
T
D
E
H
Chimpanzee
Pan troglodytes
XP_001153728
379
43666
Y340
R
K
K
V
L
A
Q
Y
Y
T
V
T
D
E
H
Rhesus Macaque
Macaca mulatta
XP_001096675
379
43478
Y340
R
K
K
V
L
A
Q
Y
Y
T
V
T
D
E
H
Dog
Lupus familis
XP_536242
380
42964
Y341
R
K
K
V
L
A
Q
Y
Y
A
V
T
N
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q08288
388
43717
Y349
K
K
K
V
I
A
Q
Y
H
A
V
M
N
D
H
Rat
Rattus norvegicus
Q6AYK5
386
43662
Y347
K
K
K
V
I
A
Q
Y
H
A
V
M
S
D
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511111
391
45222
Y351
R
K
K
V
L
A
Q
Y
Y
A
V
T
A
S
G
Chicken
Gallus gallus
XP_420792
364
42082
Y325
R
K
K
V
I
A
Q
Y
Y
A
V
A
G
E
H
Frog
Xenopus laevis
NP_001086609
360
41600
Y321
R
K
K
V
L
A
H
Y
Y
A
V
S
S
E
H
Zebra Danio
Brachydanio rerio
NP_956973
320
37238
Y280
R
K
K
V
L
A
A
Y
Y
S
F
S
G
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610573
281
32090
D247
A
K
H
L
S
V
E
D
L
N
E
K
Q
A
K
Honey Bee
Apis mellifera
XP_623803
246
28455
G212
K
L
N
N
S
E
N
G
I
D
T
I
N
N
D
Nematode Worm
Caenorhab. elegans
Q09464
253
28497
S219
K
A
I
I
E
E
L
S
A
A
G
A
A
S
D
Sea Urchin
Strong. purpuratus
XP_780603
1141
125640
L719
F
E
L
I
G
N
Q
L
V
V
H
V
K
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37263
153
17720
S119
I
E
L
H
K
G
K
S
L
Y
K
I
L
K
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
97.3
76.8
N.A.
72.6
74.8
N.A.
62.9
55.6
53.2
43.7
N.A.
27.1
26.9
29.8
20.2
Protein Similarity:
100
98.9
98.6
85.5
N.A.
83.5
86.5
N.A.
76.2
71.7
69.9
64.3
N.A.
46.9
40.1
44.8
28.1
P-Site Identity:
100
100
100
86.6
N.A.
53.3
53.3
N.A.
73.3
73.3
73.3
53.3
N.A.
6.6
0
0
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
80
N.A.
73.3
80
80
73.3
N.A.
20
13.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
27.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
67
7
0
7
47
0
14
14
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
0
7
0
0
20
20
14
% D
% Glu:
0
14
0
0
7
14
7
0
0
0
7
0
0
40
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
7
7
0
7
0
0
7
0
14
0
7
% G
% His:
0
0
7
7
0
0
7
0
14
0
7
0
0
0
54
% H
% Ile:
7
0
7
14
20
0
0
0
7
0
0
14
0
0
0
% I
% Lys:
27
74
67
0
7
0
7
0
0
0
7
7
7
14
7
% K
% Leu:
0
7
14
7
47
0
7
7
14
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% M
% Asn:
0
0
7
7
0
7
7
0
0
7
0
0
20
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
60
0
0
0
0
0
7
0
0
% Q
% Arg:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% R
% Ser:
0
0
0
0
14
0
0
14
0
7
0
14
14
14
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
20
7
34
0
0
7
% T
% Val:
0
0
0
67
0
7
0
0
7
7
60
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
54
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _